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ISSN 1462-2416

LONG COVID-A hypothesis for understanding the biological basis and pharmacological treatment strategy

Moving forward, the integration of biochemical reconstitution approaches, live-cell PTM biosensors, and spatiotemporal manipulation tools such as STRIP, together with the development of selective small-molecule modulators of glutamylation, will be essential for mapping this modification with high temporal and spatial precision and for establishing causal links between specific glutamylation patterns and defined cellular outputs